Hypersensitivity to the active substance or to any of the excipients.
AV block of 2nd or 3rd degree, bundle branch block, atrial conduction defects and sinus disease.
Unstable hemodynamic conditions.
Heart failure.
Systolic dysfunction of the left ventricle.
Interstitial lung disease.
History of liver or lung disease under treatment with amiodarone.
Co-administration of potent CYP3A4 inhibitors such as ketoconazole, itraconazole, voriconazole, posaconazole, telithromycin, clarithromycin, ritonavir and cyclosporine (see "Interactions").
Drugs inducing torsades de pointes such as phenothiazines, cisapride, bepridil, tricyclic antidepressants, terfenadine and certain oral macrolides such as erythromycin, Class I and III antiarrhythmics (see "Interactions").