Atrial fibrillation (AF)

Diagnostic and therapeutic approach

  1. Diagnosis
  2. Treatment
  3. Scores
  4. Pharmaceuticals
  5. ESC recommandations

Pharmaceuticals

  1. Amiodarone
  2. Oral anticoagulants
  3. ß-Blockers
  4. Dabigatran (Pradaxa)
  5. Digitalis (Digoxine)
  6. Diltiazem (Dilzem)
  7. Dronedarone (Multaq)
  8. Flecainide (Tambocor)
  9. Ibutilide (Corvert)
  10. Propafenone (Rytmonorm)
  11. Rivaroxaban (Xarelto)
  12. Sotalol (Sotalex)
  13. Verapamil (Isoptin)
  14. Vernakalant (Brinavess)
  15. Apixaban (Eliquis)
  16. Edoxaban (Lixiana)

Ibutilide (Corvert)

(Corvert)

Charge

If weight > 60 kg: 10 ml in 10 min.

If weight < 60 kg: 0.1 ml / kg 10 min.

Can be repeated after 10 minutes. if arrhythmia persists.

1 ml in 10 min = 1 mg

Contra-indications

  • Hypersensitivity to ibutilide fumarate or to another component.
  • Polymorphic ventricular tachycardia (eg torsades de pointes).
  • Myocardial infarction within the previous 3 months; unstable angina
  • Severe hypotension
  • Hypokalemia (< 4.0 mmol / l)
  • QT interval > 440 msec
  • Simultaneous treatment with antiarrhythmic classes Ia and III or with other substances prolonging the QT interval (eg phenothiazines, tricyclic antidepressants and tetracyclic Some H1 receptor antagonists).

http://www.drugs.com/mtm/ibutilide.html