Edoxaban (Lixiana)

(Lixiana)

Dosage

60 mg / day or 30 mg / day if renal impairment or weight <60 kg.

Absolute contra-indications

• Hypersensitivity to the active substance or to any of the excipients.
• Acute hemorrhage, clinically significant.
• Patients with hepatic disease associated with coagulopathy and a risk of significant bleeding.
• Injury or illness, if considered at significant risk of major bleeding.
• Pregnancy and breast feeding.
• Attention to drug interactions and inhibitors of CYP3A4 and / or P-gp.

Compendium